Larcos G, Baillon L G
Department of Nuclear Medicine and Ultrasound, Westmead Hospital, Sydney, New South Wales, Australia.
Australas Radiol. 1998 Nov;42(4):341-3. doi: 10.1111/j.1440-1673.1998.tb00534.x.
Asian women have been reported to have lower bone mineral density (BMD) than Caucasians, but this could be due to body habitus rather than ethnicity. The purpose of the present study was to determine whether Australian women of Asian descent have intrinsically dissimilar BMD compared to Australian women of Caucasian origin. We compared Australian Asian (n = 36) and Caucasian (n = 304) women who were referred for bone densitometry and in whom disorders or medications known to interfere with bone metabolism were excluded. Covariables including age, postmenopausal status, years since menopause (YSM), alcohol and smoking consumption, family history, current exercise levels, height, weight, body mass index (BMI) and Asian origin were analysed by multivariate linear regression to determine the independent predictors of BMD in the spine, hip and distal radius. The BMD in the spine (R2 = 0.31), hip (R2 = 0.27) and distal radius (R2 = 0.31) were associated with YSM (all sites), postmenopausal status, weight and smoking (spine and hip), BMI (spine and wrist), family history (hip) and height (wrist). The BMD at these sites were similar for Asian and Caucasian women after adjusting for these variables. Thus, Asian-Australians have similar BMD to Caucasian-Australians after adjusting for potential confounding variables. Bone mineral density is independently related to a number of clinical and lifestyle-related factors, but not ethnicity.
据报道，亚洲女性的骨矿物质密度（BMD）低于白种人，但这可能是由于身体体型而非种族原因。本研究的目的是确定与澳大利亚白种女性相比，澳大利亚亚裔女性的BMD是否存在本质差异。我们比较了36名澳大利亚亚裔女性和304名澳大利亚白种女性，这些女性均因骨密度测量而被转诊，且排除了已知会干扰骨代谢的疾病或药物因素。通过多元线性回归分析年龄、绝经后状态、绝经年限（YSM）、饮酒和吸烟情况、家族史、当前运动水平、身高、体重、体重指数（BMI）和亚洲血统等协变量，以确定脊柱、髋部和桡骨远端BMD的独立预测因素。脊柱（R2 = 0.31）、髋部（R2 = 0.27）和桡骨远端（R2 = 0.31）的BMD与YSM（所有部位）、绝经后状态、体重和吸烟（脊柱和髋部）、BMI（脊柱和腕部）、家族史（髋部）和身高（腕部）相关。在对这些变量进行调整后，亚洲女性和白种女性在这些部位的BMD相似。因此，在对潜在混杂变量进行调整后，澳大利亚亚裔女性的BMD与澳大利亚白种女性相似。骨矿物质密度与许多临床和生活方式相关因素独立相关，但与种族无关。
