Oury A P, Demarche M, Hoyoux C, Erpicum P
Service de Chirurgie pédiatrique, CHR Citadelle.
Rev Med Liege. 1998 Sep;53(9):537-40.
Sacro-coccygeal teratoma is the tumor which is most frequently diagnosed in infants. In spite of the sometimes spectacular appearance of the tumor, the surgical treatment generally permits a definitive cure of the disease without any significant functional or esthetic sequellae. The risk of malignant recurrence, even after removal of an apparently benign mass is not totally excluded and may imply to resort to combined treatment by surgery and chemotherapy. The baby must be carefully followed-up and the serum levels of alpha-foetoprotein (a specific tumor marker), and sometimes beta-HCG must be regularly measured. Local surveillance is mandatory to prevent any loss of time in case of recurrence.
骶尾部畸胎瘤是婴儿中最常被诊断出的肿瘤。尽管肿瘤有时外观惊人,但手术治疗通常能使疾病得到根治,且不会留下任何明显的功能或美观后遗症。即使切除了看似良性的肿块,也不能完全排除恶性复发的风险,这可能意味着需要采用手术和化疗相结合的治疗方法。必须对婴儿进行仔细的随访,并定期测量血清甲胎蛋白(一种特定的肿瘤标志物)水平,有时还需测量β-人绒毛膜促性腺激素水平。必须进行局部监测,以防复发时耽误治疗时机。