Robinson D N, O'Brien K, Kumar R, Morton N S
Department of Anaesthesia, Royal Hospital for Sick Children, Yorkhill, Glasgow, Scotland, UK.
Paediatr Anaesth. 1998;8(6):467-71. doi: 10.1046/j.1460-9592.1998.00275.x.
Forty healthy children, aged between two and 12 years of age undergoing elective surgery where the anaesthetic technique involved tracheal intubation followed by spontaneous ventilation were studied. Induction of anaesthesia was with either alfentanil 15 micrograms.kg-1 or remifentanil 1 microgram.kg-1 followed by propofol 4 mg.kg-1 to which lignocaine 0.2 mg.kg-1 had been added. Intubating conditions were graded on a four point scale for ease of laryngoscopy, vocal cord position, degree of coughing, jaw relaxation and limb movement. All children were successfully intubated at the first attempt. There were no significant differences in the assessments of intubating conditions between the two groups. Arterial blood pressure and heart changes were similar in the two groups with both alfentanil and remifentanil attenuating the haemodynamic response to tracheal intubation. The time taken to resumption of spontaneous ventilation was similar in both groups.
对40名年龄在2至12岁之间接受择期手术的健康儿童进行了研究，这些手术的麻醉技术包括气管插管后自主通气。麻醉诱导采用阿芬太尼15微克/千克或瑞芬太尼1微克/千克，随后给予丙泊酚4毫克/千克，并添加了利多卡因0.2毫克/千克。根据喉镜检查的难易程度、声带位置、咳嗽程度、下颌松弛程度和肢体运动，对插管条件进行四分制评分。所有儿童均首次成功插管。两组之间插管条件的评估没有显著差异。两组的动脉血压和心率变化相似，阿芬太尼和瑞芬太尼均能减轻气管插管引起的血流动力学反应。两组恢复自主通气的时间相似。
