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[囊状纵隔淋巴管瘤瘤内注射OK-432治疗的成功病例报告]

[A successful case report on intralesional OK-432 therapy for cystic mediastinal lymphangiomas].

作者信息

Okubo T, Shimada T, Narita Y, Okushiba T, Douke M, Takahashi T, Okushiba S, Motohara T, Katou H

机构信息

Second Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.

出版信息

Kyobu Geka. 1998 Nov;51(12):1017-21.

PMID:9838780
Abstract

A 42-years-old female was referred to the university hospital because of cystic lesions of the right superior mediastinum. Drainage tube was found at right supraclavicular fossa with prolonged lymphatic discharge. We diagnosed this case as a benign cystic lymphangiomas with CT scan and CT scan with cystography and chemical analysis of the contents of the cyst. Intralesional OK-432 therapy for cystic mediastinal lymphangioma was performed. OK-432 was administered through intralesionally placed drainage tube. Excellent result was obtained. A few weeks later, residual lymphatic discharge through drainage tube became stopped. No expansion of the mediastinal cyst was found after drainage tube removal. Intralesional OK-432 therapy for cystic mediastinal lymphangioma was very effective and useful, it should be recommended for the management of the first choice of therapeutic method for cystic mediastinal lymphangioma because of no neurological deficit after this treatment.

摘要

一名42岁女性因右上纵隔囊性病变被转诊至大学医院。在右锁骨上窝发现引流管,伴有持续性淋巴液引流。我们通过CT扫描、CT扫描联合囊肿造影以及囊肿内容物化学分析,将该病例诊断为良性囊性淋巴管瘤。对囊性纵隔淋巴管瘤进行了瘤内注射OK-432治疗。OK-432通过瘤内放置的引流管给药。取得了优异的效果。几周后,通过引流管的残余淋巴液引流停止。拔除引流管后未发现纵隔囊肿扩大。瘤内注射OK-432治疗囊性纵隔淋巴管瘤非常有效且实用,由于该治疗后无神经功能缺损,应推荐作为囊性纵隔淋巴管瘤治疗的首选方法。

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Kyobu Geka. 1998 Nov;51(12):1017-21.
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Is intralesional injection of OK-432 effective in the treatment of lymphangioma in children?瘤内注射溶链菌制剂对儿童淋巴管瘤的治疗是否有效?
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