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白细胞介素13由人头颈部肿瘤分泌，在体外不调节其生长。

Interleukin 13 is secreted by human head and neck tumours and does not modulate their growth in vitro.

作者信息

Mehrotra R

机构信息

Department of Pathology, M.L.N. Medical College, Allahabad, India.

出版信息

Indian J Exp Biol. 1998 Aug;36(8):805-7.

PMID:9838882
Abstract

Expression of interleukin-13 (IL-13) has been examined in head and neck cancer cell lines. This interleukin was expressed by all human head and neck carcinoma cells studied, though in varying degrees. The effect of exogenous IL-13 on growth of squamous cell carcinomas of the head and neck cell lines was also studied. It was found that this cytokine did not modulate the proliferation of four cell lines studied. These results demonstrate that human squamous cell carcinoma of the head and neck secrete IL-13.

摘要

白介素-13（IL-13）在头颈癌细胞系中的表达已得到研究。在所研究的所有人类头颈癌细胞中均有该白介素的表达，不过表达程度各异。同时也对外源性IL-13对头颈癌细胞系鳞状细胞癌生长的影响进行了研究。结果发现，这种细胞因子并未调节所研究的四种细胞系的增殖。这些结果表明，人类头颈鳞状细胞癌会分泌IL-13。

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