Central nervous system tumors: what have we learned and where are we heading?

Molecular biology, laboratory and human studies, and clinical trials have furthered knowledge about the pathogenesis, behavior, and treatment of brain tumors. Technical advances such as functional imaging, computer-guided stereotactic surgical devices, and radiosurgery have improved treatment. The future promises continued progress, with the exploration of areas such as new chemotherapy delivery systems, gene therapy, boron capture therapy, and photodynamic therapy.