Forbes T R, Kapadia S E
Am J Anat. 1976 Nov;147(3):325-8. doi: 10.1002/aja.1001470306.
Pellets of glass (control), progesterone (P), testosterone (T), and estradiol-17beta (E) were placed on the mesentery or subcutaneously in the flank in ovariectomized (O) and ovariectomized-hysterectomized (OH) mice, insuring that all or most of the hormone would pass through the superior mesinteric or circumflex iliac veins. After 21 days the diameters of these and of the ovarian, uterine, and femoral veins and inferior vena cava were measured at autopsy. T and E caused significant enlargement of the uteri; E was also responsible for bladder distention. The ovarian and uterine veins enlarged significantly in mice treated with T and E as compared to the controls. All other veins failed to respond to P, T, and E. The evidence demonstrates a specific response of ovarian and uterine veins in O and OH mice to T and E.
将玻璃丸（对照）、孕酮（P）、睾酮（T）和雌二醇 - 17β（E）置于去卵巢（O）和去卵巢 - 子宫切除（OH）小鼠的肠系膜上或侧腹皮下，确保所有或大部分激素会通过肠系膜上静脉或旋髂静脉。21天后，在尸检时测量这些静脉以及卵巢静脉、子宫静脉、股静脉和下腔静脉的直径。T和E导致子宫显著增大；E还导致膀胱扩张。与对照组相比，用T和E处理的小鼠的卵巢静脉和子宫静脉显著增粗。所有其他静脉对P、T和E均无反应。证据表明，O和OH小鼠的卵巢静脉和子宫静脉对T和E有特异性反应。
