De Maria N, Colantoni A, Van Thiel D H
Transplantation Center, University of Kentucky, Lexington 40536, USA.
Hepatogastroenterology. 1998 Sep-Oct;45(23):1364-8.
The experience from many transplant centers has shown that orthotopic liver transplantation is a safe and successful procedure for the treatment of end-stage chronic alcoholic liver disease. Once an appropriate psycho-medical evaluation is completed and patients are chosen carefully for abstinence, the survival rate of alcoholics who undergo liver transplantation is equal if not better than that of individuals transplanted for other causes of liver disease. While the initial ostracism of alcoholics from transplant centers no longer exists, the issues of recidivism and disease recurrence remain as concerns. The available data on liver transplantation for alcoholics, recidivism, and long-term survival are reviewed.
许多移植中心的经验表明，原位肝移植是治疗终末期慢性酒精性肝病的一种安全且成功的手术。一旦完成适当的心理医学评估并谨慎挑选戒酒的患者，接受肝移植的酗酒者的存活率即便不比因其他肝病原因接受移植的个体更好，至少也是相当的。虽然酗酒者最初在移植中心受到的排斥已不复存在，但复饮和疾病复发问题仍是令人担忧的方面。本文对酗酒者肝移植、复饮及长期生存的现有数据进行了综述。
