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主动脉缩窄合并严重主动脉瓣关闭不全时的初次球囊扩张术。

Primary balloon dilatation in coarctation of the aorta complicated by severe aortic insufficiency.

作者信息

De Meester C, Budts W, Gewillig M, Daenen W, Van de Werf F

机构信息

Department of Cardiology, Gasthuisberg University Hospital, Leuven, Belgium.

出版信息

Acta Cardiol. 1998;53(4):231-4.

PMID:9842410
Abstract

The combination of coarctation of the aorta in the presence of severe aortic insufficiency poses a serious clinical problem. Although successful single- and two-stage repair for combined coarctation in the presence of severe aortic regurgitation has been described, the surgical management of this lesion remains particularly difficult. The analysis of larger series of patients operated upon for coarctation reveals significant early mortality rate in patients with associated severe aortic insufficiency. Although the exact cause of the acute left ventricular failure remains unclear and is a matter of debate, one can assume that changes in the haemodynamics, resulting in global myocardial ischaemia from impaired coronary blood supply or a massive volume overload of the left ventricle after the correction of the coarctation, could have led to myocardial irritability and left ventricular failure. We present a three-stage repair with subtotal relief of the coarctation by balloon angioplasty and stenting first; elective aortic valve replacement in a second stage and finally total balloon dilatation of the residual stenosis at the previously subtotal dilated coarcted segment.

摘要

主动脉缩窄合并严重主动脉瓣关闭不全是一个严重的临床问题。虽然已有关于在严重主动脉反流情况下成功进行单阶段和两阶段联合缩窄修复的报道,但这种病变的外科治疗仍然特别困难。对大量接受主动脉缩窄手术的患者进行分析发现,伴有严重主动脉瓣关闭不全的患者早期死亡率很高。虽然急性左心室衰竭的确切原因尚不清楚,仍是一个有争议的问题,但可以推测,血流动力学的变化,导致冠状动脉供血受损引起的全身性心肌缺血,或在主动脉缩窄矫正后左心室大量容量超负荷,可能导致心肌应激性增加和左心室衰竭。我们提出一种三阶段修复方法,首先通过球囊血管成形术和支架置入术部分缓解缩窄;第二阶段进行择期主动脉瓣置换,最后对先前部分扩张的缩窄段残余狭窄进行完全球囊扩张。

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