Moussaoui O, Ménard P
Service de Chirurgie Maxillo-Faciale et Stomatologie, Hôpital Ambroise Paré, Boulogne.
Rev Stomatol Chir Maxillofac. 1998 Oct;99(3):132-7.
Leiomyosarcoma (LMS) accounts for 7% of all smooth tissue sarcomas. The rarity of smooth muscle cells in the oral cavity makes LMS a rare tumor in this localization. We report a case of gingival LMS in a 43-year-old woman. We reviewed 23 cases of LMS or the oral cavity report in the literature since 1980. Age of occurrence varied from 2.5 to 63 years with a predominance in the 20 to 30 years age range. In two-thirds of the cases, the first symptom was the development of a painful mass. In half the mass developed in the maxilla and in one-quarter it occurred in the gingival mucosa alone. In nearly all cases treatment was wide excision resection. Surgery with chemotherapy and radiotherapy is reserved for high-grade or recurrent leiomyosarcoma.
平滑肌肉瘤(LMS)占所有软组织肉瘤的7%。口腔中平滑肌细胞的稀缺性使得LMS在该部位成为一种罕见肿瘤。我们报告一例43岁女性的牙龈LMS病例。我们回顾了自1980年以来文献中报道的23例口腔LMS病例。发病年龄从2.5岁至63岁不等,以20至30岁年龄范围为主。在三分之二的病例中,首发症状是出现疼痛性肿块。一半的肿块发生在上颌骨,四分之一仅发生在牙龈黏膜。几乎所有病例的治疗方法都是广泛切除。手术联合化疗和放疗用于高级别或复发性平滑肌肉瘤。