阿苯达唑治疗眼眶囊尾蚴病后发生的视神经炎。
Optic neuritis following albendazole therapy for orbital cysticercosis.
作者信息
Tandon R, Sihota R, Dada T, Verma L
机构信息
Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
出版信息
Aust N Z J Ophthalmol. 1998 Nov;26(4):339-41. doi: 10.1111/j.1442-9071.1998.tb01341.x.
PURPOSE
To report the occurrence of optic neuritis following oral albendazole therapy for orbital cysticercosis.
METHODS
Two patients having definitively diagnosed orbital cysticercosis at the orbital apex developed an acute visual loss 1 week after initiation of oral albendazole. Ultrasonography and magnetic resonance imaging determined that the cause was optic neuritis due to disorganization of the cyst with inflammation of the adjacent optic nerve.
RESULTS
Oral corticosteroids (prednisolone 1 mg/kg per day) given for a period of 4 weeks led to resolution of the optic neuritis, with full visual recovery.
CONCLUSION
Corticosteroids should be given in addition to albendazole in the treatment of orbital cysticercosis when cysts are in close proximity to the optic nerve.
目的
报告口服阿苯达唑治疗眼眶囊尾蚴病后发生视神经炎的情况。
方法
两名在眶尖确诊为眼眶囊尾蚴病的患者在开始口服阿苯达唑1周后出现急性视力丧失。超声检查和磁共振成像确定病因是囊肿破裂伴相邻视神经炎症导致的视神经炎。
结果
给予为期4周的口服皮质类固醇（泼尼松龙1毫克/千克/天）使视神经炎消退，视力完全恢复。
结论
当囊肿紧邻视神经时，在治疗眼眶囊尾蚴病时除阿苯达唑外还应给予皮质类固醇。
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