• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

血细胞中前列腺特异性膜抗原的巢式逆转录聚合酶链反应的应用：对前列腺腺癌患者血源性肿瘤细胞检测的意义

The use of nested RT-PCR of prostate-specific membrane antigen in blood cells: implications for the detection of haematogenous neoplastic cells in patients with prostate adenocarcinoma.

作者信息

Lucotte G, Mercier G, Burckel A

机构信息

Regional Center of Neurogenetics, Service of Neurology, Maison Blanche Hospital, 45 rue Cognacq-Jay, Reims, France.

出版信息

Mol Cell Probes. 1998 Dec;12(6):421-5. doi: 10.1006/mcpr.1998.0201.

DOI:10.1006/mcpr.1998.0201
PMID:9843660
Abstract

The aim of this study was to determine the presence of haematogenous neoplastic cells in patients with prostate cancer. Circulating prostate cells can be detected in cancer patients by using a nested-reverse transcriptase-polymerase chain reaction assay (RT-PCR), for prostate-specific membrane (PSM) antigen mRNA. This sensitive nested RT-PCR assay may play a crucial role in the administration of adjuvant therapy of patients with prostate adenocarcinoma.

摘要

本研究的目的是确定前列腺癌患者中是否存在血源性肿瘤细胞。通过使用巢式逆转录聚合酶链反应分析（RT-PCR）检测前列腺特异性膜（PSM）抗原mRNA，可在癌症患者中检测到循环前列腺细胞。这种灵敏的巢式RT-PCR分析可能在前列腺腺癌患者辅助治疗的实施中发挥关键作用。

相似文献

1
The use of nested RT-PCR of prostate-specific membrane antigen in blood cells: implications for the detection of haematogenous neoplastic cells in patients with prostate adenocarcinoma.血细胞中前列腺特异性膜抗原的巢式逆转录聚合酶链反应的应用：对前列腺腺癌患者血源性肿瘤细胞检测的意义
Mol Cell Probes. 1998 Dec;12(6):421-5. doi: 10.1006/mcpr.1998.0201.
2
Detection of blood-borne cells in colorectal cancer patients by nested reverse transcription-polymerase chain reaction for carcinoembryonic antigen messenger RNA: longitudinal analyses and demonstration of its potential importance as an adjunct to multiple serum markers.通过巢式逆转录聚合酶链反应检测结直肠癌患者血源细胞中的癌胚抗原信使核糖核酸：纵向分析及其作为多种血清标志物辅助手段的潜在重要性的论证
Cancer Res. 2001 Mar 15;61(6):2523-32.
3
Detection of prostate cancer cells circulating in peripheral blood by reverse transcription-PCR for hKLK2.通过逆转录聚合酶链反应检测外周血中循环的前列腺癌细胞以检测人激肽释放酶2。
Cancer Res. 1997 Oct 1;57(19):4167-70.
4
Detection of micrometastatic prostate cancer cells in the lymph nodes by reverse transcriptase polymerase chain reaction is predictive of biochemical recurrence in pathological stage T2 prostate cancer.通过逆转录聚合酶链反应检测淋巴结中的微转移前列腺癌细胞可预测病理分期为T2期前列腺癌的生化复发。
J Urol. 2000 Apr;163(4):1183-8.
5
Sensitive detection of small cell lung carcinoma cells by reverse transcriptase-polymerase chain reaction for prepro-gastrin-releasing peptide mRNA.通过逆转录聚合酶链反应对胃泌素释放肽原mRNA进行小细胞肺癌细胞的灵敏检测。
Cancer. 2003 May 15;97(10):2504-11. doi: 10.1002/cncr.11378.
6
Reverse transcription-polymerase chain reaction detection of prostate-specific antigen, prostate-specific membrane antigen, and prostate stem cell antigen in one milliliter of peripheral blood: value for the staging of prostate cancer.一毫升外周血中前列腺特异性抗原、前列腺特异性膜抗原和前列腺干细胞抗原的逆转录聚合酶链反应检测：对前列腺癌分期的价值
Clin Cancer Res. 2002 Jun;8(6):1794-9.
7
Early postoperative peripheral blood reverse transcription PCR assay for prostate-specific antigen is associated with prostate cancer progression in patients undergoing radical prostatectomy.前列腺癌根治术后患者早期外周血前列腺特异性抗原逆转录聚合酶链反应检测与前列腺癌进展相关。
Cancer Res. 2003 Sep 15;63(18):5874-8.
8
Optimization of the reverse transcriptase polymerase chain reaction for the detection of circulating prostate cells.用于检测循环前列腺细胞的逆转录聚合酶链反应的优化
Br J Cancer. 2000 Oct;83(8):992-7. doi: 10.1054/bjoc.2000.1417.
9
The use of real-time reverse transcription-PCR for prostate-specific antigen mRNA to discriminate between blood samples from healthy volunteers and from patients with metastatic prostate cancer.使用实时逆转录聚合酶链反应检测前列腺特异性抗原信使核糖核酸，以区分健康志愿者和转移性前列腺癌患者的血样。
Clin Cancer Res. 2004 Nov 15;10(22):7511-9. doi: 10.1158/1078-0432.CCR-04-0166.
10
Heterogeneous expression of MAGE-A genes in occult disseminated tumor cells: a novel multimarker reverse transcription-polymerase chain reaction for diagnosis of micrometastatic disease.MAGE-A基因在隐匿性播散肿瘤细胞中的异质性表达：一种用于诊断微转移疾病的新型多标志物逆转录-聚合酶链反应
Cancer Res. 2002 Jan 1;62(1):251-61.