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[直径小于15毫米的肺小腺癌切除标本的计算机断层扫描分析——影像学与组织学特征的相关性]

[Computed tomography analysis of resected small adenocarcinomas of the lung less than 15 mm in diameter--correlation of radiologic and histologic characteristics].

作者信息

Shimizu K, Yamada K, Noda K

机构信息

Second Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan.

出版信息

Nihon Kokyuki Gakkai Zasshi. 1998 Aug;36(8):672-8.

PMID:9844385
Abstract

To analyze the radiographic characteristics of small adenocarcinomas of the lung that can be detected by computed tomography (CT), 46 resected small peripheral adenocarcinomas measuring less than 15 mm in diameter were retrospectively reviewed, and the marginal and internal findings and surrounding vessels of the tumors as shown on thin-section CT images were correlated with six histologic classifications (types A-F) as defined by Noguchi et al. The adenocarcinoma CT images were classified into two patterns: a solid-density type (n = 21) and an air-containing type (n = 25). The lesions of the air-containing type were further divided into two different growth patterns: a complete air-containing type (n = 12) and an incomplete air-containing type (n = 13). The solid-density adenocarcinomas shown in the CT images fell mainly into the C, D, F and Noguchi classifications. Although one sample in the complete air-containing category was type C, the rest were type A. The incomplete air-containing category included 4 type As and 9 type Bs. The CT findings for the 24 adenocarcinomas in the air-containing category (96%) showed an opaque ground-glass internal texture. Plural vascular involvement was observed in all 46 adenocarcinomas examined. Our results suggest that thin-section CT findings can play an important role in differentiating lung cancer and increasing our knowledge of the radiologic and pathologic correlations.

摘要

为分析计算机断层扫描(CT)可检测出的肺小腺癌的影像学特征,我们回顾性研究了46例直径小于15mm的周围型小腺癌,这些腺癌均已切除。薄层CT图像上显示的肿瘤边缘、内部表现及周围血管情况与野口等人定义的六种组织学分类(A - F型)相关。腺癌的CT图像分为两种类型:实性密度型(n = 21)和含气型(n = 25)。含气型病变进一步分为两种不同的生长模式:完全含气型(n = 12)和不完全含气型(n = 13)。CT图像上显示的实性密度腺癌主要属于C、D、F型及野口分类。完全含气型中一个样本为C型,其余为A型。不完全含气型包括4个A型和9个B型。含气型中的24例腺癌(96%)的CT表现为内部质地呈不透明磨玻璃样。在所有46例被检查的腺癌中均观察到多支血管受累。我们的结果表明,薄层CT表现对于鉴别肺癌以及增进我们对影像学与病理学相关性的认识可起到重要作用。

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