Bauduer F
Service des Maladies du Sang, Centre Hospitalier de la Côte Basque, Bayonne, France.
Hematol Cell Ther. 1998 Oct;40(5):189-91.
Autoimmune neutropenia (AIN) is a rare hematological disorder for which no standard treatment has been established so far. A brief review of the literature is presented herein concerning the use of G-CSF in this indication. The good results in terms of neutrophils increment and infection prophylaxis render G-CSF attractive for treating AIN. Hypotheses explaining its mechanisms of action are also discussed.
自身免疫性中性粒细胞减少症（AIN）是一种罕见的血液系统疾病，目前尚未确立标准治疗方法。本文简要回顾了有关粒细胞集落刺激因子（G-CSF）用于该适应症的文献。G-CSF在增加中性粒细胞和预防感染方面取得的良好效果使其成为治疗AIN的有吸引力的选择。文中还讨论了解释其作用机制的假说。
