Hammock P D, Freeman D E, Baker G J
Department of Veterinary Clinical Medicine, University of Illinois, College of Veterinary Medicine, Urbana 61802, USA.
Vet Surg. 1998 Nov-Dec;27(6):547-54. doi: 10.1111/j.1532-950x.1998.tb00530.x.
To examine the efficacy of psyllium mucilloid in evacuating sand from the equine large intestine.
12 clinically healthy pony geldings.
Twelve ponies were assigned to 2 groups of six each. One group was treated with psyllium and the second was a control group. All ponies had an exploratory celiotomy and 10 g/kg body weight of sand was placed into the cecum. Ponies were fed a grain mixture alone at 1 g/kg (controls), a grain mixture plus psyllium pellets, each at 1 g/kg body weight (3 ponies), or fed a grain mixture and given psyllium powder by nasogastric tube at 1 g/kg body weight divided into two daily doses in 3 L of water (3 ponies). Radiographs were taken on days 1 (3 per group), 5 (all ponies), and 11 (3 per group) to monitor sand transit through the large intestine. Ponies were euthanatized 11 days after surgery. Sand was collected from the contents of the cecum, ventral colon, dorsal colon, and small colon. Dry weight of the recovered sand was compared between the two treatment groups as a percentage of the dry weight of sand placed in the cecum.
No significant differences were detected in the mean percentage of sand recovered between the two treatment groups (P < .05), with 39.2% recovered in ponies treated with psyllium and 27.4% recovered in control ponies.
Psyllium mucilloid had no apparent effect on sand evacuation from the equine large intestine. When intake of sand is prevented, the equine large intestine can reduce and possibly eliminate its sand burden.
研究车前草黏液质在排出马属动物大肠内沙子方面的疗效。
12匹临床健康的雄性小马。
12匹小马被分为2组，每组6匹。一组用车前草治疗，另一组为对照组。所有小马均接受了剖腹探查术，并将10克/千克体重的沙子放入盲肠。对照组小马仅喂食1克/千克体重的谷物混合物，3匹小马喂食1克/千克体重的谷物混合物加车前草颗粒，另外3匹小马喂食谷物混合物并通过鼻胃管给予1克/千克体重的车前草粉末，分两次每日剂量溶于3升水中。在第1天（每组3匹）、第5天（所有小马）和第11天（每组3匹）拍摄X光片，以监测沙子在大肠中的传输情况。术后11天对小马实施安乐死。从盲肠、腹侧结肠、背侧结肠和小结肠内容物中收集沙子。比较两个治疗组回收沙子的干重占放入盲肠沙子干重的百分比。
两个治疗组回收沙子的平均百分比无显著差异（P < 0.05），服用车前草的小马回收了39.2%的沙子，对照小马回收了27.4%的沙子。
车前草黏液质对排出马属动物大肠内的沙子没有明显效果。当防止沙子摄入时，马属动物的大肠可以减轻并可能消除其沙子负担。
