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[用于研究甲状腺功能减退症的体内和体外放射性同位素测试分析。对正常受试者和甲状腺功能减退症患者常规检查参数的统计学研究]

[Analysis of in vivo and in vitro radioisotopic tests for studying hypothyroidism. Statistical study of parameters coming from routine investigations in normal subjects and hypothyroid patients].

作者信息

Vallée G, Fandard J, Morin M, Nouchy J

出版信息

Ann Biol Clin (Paris). 1976;34(3):173-90.

PMID:984524
Abstract

This report analyses quantitative data collected during spontaneous examination in normal subjects and in hypothyroid subjects, attempting to determine what figures obtained in this way can provide in the diagnosis of this disease. 125I tests in vitro today play a very important role and suffice der detection provided radio-immunoassay is carried out, whether the latter concerns iodine hormones or the thyreotropic pituitary hormone and provided the diagnosis is not confirmed by one single examination. The 131I kinetic test helps in classification of the hypothyroidism. Naturally, only further tests will permit us to determine certain causes (thyroid scan, Querido's test, TRF test, anionic competition, immunological study, etc.). Chemical estimations of stable iodine (127I) no longer have any place in this routine assessment, except that the total iodine is essential to interpret the kinetics in vivo.

摘要

本报告分析了在正常受试者和甲状腺功能减退受试者的自发检查过程中收集的定量数据,试图确定以这种方式获得的数据在该疾病的诊断中能提供什么信息。如今,体外125I检测发挥着非常重要的作用,只要进行放射免疫测定,无论检测的是碘激素还是促甲状腺垂体激素,并且只要单次检查不能确诊,就足以进行检测。131I动力学检测有助于甲状腺功能减退症的分类。当然,只有进一步的检测才能使我们确定某些病因(甲状腺扫描、奎里多试验、促甲状腺激素释放因子试验、阴离子竞争、免疫学研究等)。稳定碘(127I)的化学测定在这种常规评估中已不再有任何作用,除非总碘对于解释体内动力学至关重要。

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