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仅基于术前无创成像的血管内手术。

Endovascular surgery based solely on noninvasive preprocedural imaging.

作者信息

Levy M M, Baum R A, Carpenter J P

机构信息

Departments of Surgery and Radiology, University of Pennsylvania School of Medicine,Philadelphia, PA, USA.

出版信息

J Vasc Surg. 1998 Dec;28(6):995-1003; discussion 1003-5. doi: 10.1016/s0741-5214(98)70025-4.

Abstract

PURPOSE

Conventional pre-endovascular procedural evaluation uses both noninvasive testing and diagnostic arteriography. Diagnostic and therapeutic procedures often must be performed separately because of concerns about excessive contrast administration or inappropriate location of vascular access for the interventional procedure. We wanted to determine if patients could successfully undergo endovascular procedures based on noninvasive modalities alone.

METHODS

One hundred nineteen consecutive patients requiring intervention for lower-extremity ischemia were evaluated by means of physical examinations and segmental pressure measurements. Patients then underwent magnetic resonance angiography (MRA) to image native vessels or duplex scanning for failing bypass grafts. Suitable patients underwent endovascular procedures with "road map" arteriography, which was compared with preoperative duplex scanning or MRA findings. Costs of the conventional and noninvasive approaches were compared, on the basis of estimated hospital cost schedule.

RESULTS

Sixty consecutive endovascular procedures were performed in 56 patients (105 lesions angioplastied), either alone (30, 50%) or in combination (30, 50%) with another vascular reconstruction. Completely noninvasive evaluation was accomplished in 43 procedures (72%), either by means of duplex scanning (11, 18%) or MRA (32, 53%). Conventional arteriography (CA) was required in 2 patients (3%) because of MRA contraindications and in 1 patient because of complex previous arterial reconstruction. Fourteen patients had earlier CAs. The findings of the noninvasive modalities were confirmed in every case by means of intraoperative arteriography, and no additional lesions were revealed (no false positive or negative studies). After endovascular interventions, the mean patient ankle-brachial index (ABI) improved from 0.64 +/- 0.03 to 0.81 +/- 0.03 (P <.001) and the mean limb-status category improved from 3.4 +/- 0.2 to 0.8 +/- 0.2 (P <.001). There were 4 initial technical failures (7%), 1 morbidity (1%), and no mortalities. The noninvasive approach was less costly than if preprocedural diagnostic CA had been used, allowing $551 saved for each duplex scanning case and $235 saved for each MRA case. If the cost of a short-stay unit after a diagnostic arteriogram was included, the savings were greater: $695 saved for each duplex scanning case and $379 saved for each MRA case.

CONCLUSION

Endovascular procedures can be performed based on preprocedural noninvasive modalities alone. For patients requiring endovascular procedures, knowledge of the arterial anatomy before obtaining arterial access avoids the need for additional punctures or sessions (eg, antegrade puncture for femoral angioplasty after retrograde puncture for the diagnostic arteriogram). This approach is less costly than performing preprocedural diagnostic arteriography and avoids the hazards of arterial puncture and nephrotoxic contrast agents.

摘要

目的

传统的血管内介入术前评估同时使用非侵入性检查和诊断性血管造影。由于担心造影剂过量使用或介入操作的血管入路位置不当,诊断和治疗操作通常必须分开进行。我们想确定患者是否仅基于非侵入性检查就能成功接受血管内介入手术。

方法

对119例因下肢缺血需要干预的连续患者进行体格检查和节段性压力测量评估。然后患者接受磁共振血管造影(MRA)以对自身血管成像,或接受双功超声扫描以评估失败的旁路移植血管。合适的患者接受了带有“路线图”血管造影的血管内介入手术,并将其与术前双功超声扫描或MRA结果进行比较。根据估计的医院费用表,比较了传统方法和非侵入性方法的费用。

结果

56例患者共进行了60例连续的血管内介入手术(105处病变接受了血管成形术),其中单独进行血管内介入手术的有30例(50%),与另一血管重建手术联合进行的有30例(50%)。43例手术(72%)完成了完全非侵入性评估,其中通过双功超声扫描的有11例(18%),通过MRA的有32例(53%)。2例患者(3%)因MRA禁忌证需要进行传统血管造影(CA),1例患者因既往复杂的动脉重建手术需要进行传统血管造影。14例患者之前进行过CA。非侵入性检查的结果在每例患者中均通过术中血管造影得到证实,且未发现其他病变(无假阳性或假阴性研究)。血管内介入治疗后,患者的平均踝肱指数(ABI)从0.64±0.03提高到0.81±0.03(P<0.001),平均肢体状态分类从3.4±0.2改善到0.8±0.2(P<0.001)。有4例初始技术失败(7%),出现1例并发症(1%),无死亡病例。非侵入性方法的费用低于使用术前诊断性CA的情况,每例双功超声扫描病例节省551美元,每例MRA病例节省235美元。如果将诊断性血管造影后短期住院单元的费用计算在内,节省的费用更多:每例双功超声扫描病例节省695美元,每例MRA病例节省379美元。

结论

血管内介入手术可仅基于术前非侵入性检查进行。对于需要进行血管内介入手术的患者,在获得动脉入路前了解动脉解剖结构可避免额外的穿刺或手术(例如,在逆行穿刺进行诊断性血管造影后,再进行顺行穿刺进行股动脉血管成形术)。这种方法比进行术前诊断性血管造影成本更低,且避免了动脉穿刺和肾毒性造影剂的风险。

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