McLean I W
Department of Ophthalmic Pathology, Armed Forces Institute of Pathology, Washington, DC, USA.
Ann Diagn Pathol. 1998 Aug;2(4):264-70. doi: 10.1016/s1092-9134(98)80016-6.
The conjunctival melanoses are a group of diseases that share the common clinical findings of flat granular melanin-pigmentation of the conjunctival epithelium. Because differential diagnosis of these lesions is difficult, there is much confusion in the literature regarding taxonomy of these lesions. A histopathologic classification of benign melanosis; primary acquired melanosis with atypia, and primary acquired melanosis with melanoma is proposed. Benign melanosis should be divided based on clinical findings into complexion-associated melanosis, secondary melanosis, ephelis, and primary acquired melanosis without atypia.
结膜黑素沉着症是一组具有结膜上皮扁平颗粒状黑色素沉着这一共同临床特征的疾病。由于这些病变的鉴别诊断困难，文献中关于这些病变的分类存在很多混淆。本文提出了一种良性黑素沉着症、伴有异型性的原发性获得性黑素沉着症以及伴有黑色素瘤的原发性获得性黑素沉着症的组织病理学分类。良性黑素沉着症应根据临床特征分为肤色相关黑素沉着症、继发性黑素沉着症、雀斑以及无异型性的原发性获得性黑素沉着症。
