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[感觉神经元中枢轴突切断后足部皮肤机械感受器及坐骨神经传入神经纤维的功能特性]

[Functional characteristics of foot skin mechanoreceptors and afferent nerve fibers of the sciatic nerve after central axotomy of sensory neurons].

作者信息

Kolosova L I, Akoev G N, Moiseeva A B, Riabchikova O V

机构信息

Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1998 Aug;84(8):755-60.

PMID:9845893
Abstract

The activity of mechanoreceptors was studied in normal rats' hindfoot and compared with that of rhizotomised animals. Evoked nerve impulses were recorded from afferent fibres of the n.tibialis. A possible autonomous functioning of decentralised mechanoreceptors, even though in an altered fashion, was shown. The registered shifts comprised a decrease in sensitivity to mechanical stimulation and lower adaptive properties. The findings suggest that the underlying mechanism involves a probable lack of trophic interaction leading to interruption of a link between the CNS and the peripheral nervous system.

摘要

在正常大鼠的后足研究了机械感受器的活动,并与神经根切断动物的活动进行了比较。从胫神经的传入纤维记录诱发的神经冲动。结果表明,即使方式有所改变,去中枢化的机械感受器仍可能自主发挥功能。记录到的变化包括对机械刺激的敏感性降低和适应性特性减弱。研究结果表明,其潜在机制可能是缺乏营养相互作用,导致中枢神经系统与周围神经系统之间的联系中断。

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