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[胆碱能和单胺能脑系统活动变化后大脑动脉的肾上腺素能神经支配]

[Adrenergic innervation of the cerebral arteries following changes in the activity of cholinergic and monoaminergic brain systems].

作者信息

Pugovkin A P

机构信息

Pavlov St. Petersburg State Medical University, Russia.

出版信息

Ross Fiziol Zh Im I M Sechenova. 1998 Sep;84(9):898-905.

PMID:9845911
Abstract

Bipolar electrical nerve stimulation decreased the adrenergic innervation density and the catecholamine content in the rat isolated caudal artery. Changes in cholinesterase activity and catecholamine content in histochemically active nerves following administration of cholinesterase (AChE) inhibiting agent phosphacol, seem to reflect compensatory responses to increasing dilatory cholinergic vasomotor effects under conditions of the AChE activity. Adrenergic innervation of cerebral arteries was also studied after a 1-hr daily hypoxic sessions. These decreased the catecholamines content as compared to the control.

摘要

双相电神经刺激降低了大鼠离体尾动脉的肾上腺素能神经支配密度和儿茶酚胺含量。给予胆碱酯酶(AChE)抑制剂磷酰胆碱后,组织化学活性神经中胆碱酯酶活性和儿茶酚胺含量的变化,似乎反映了在AChE活性条件下对增强的舒张性胆碱能血管运动效应的代偿反应。在每天进行1小时的低氧训练后,也对脑动脉的肾上腺素能神经支配进行了研究。与对照组相比,这些降低了儿茶酚胺含量。

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