先天性肥厚性幽门狭窄相关黄疸（作者译）
[Jaundice associated with congenital hypertrophic pyloric stenosis (author's transl)].
作者信息
Fidalgo I, Vitoria J C, Jaquotot M R, Rodríguez Soriano J
出版信息
An Esp Pediatr. 1976 Jul-Aug;9(4):378-83.
PMID:984599
Abstract
The clinical and biological findings in six infants with congenital hypertrophic pyloric stenosis with associated jaundice are described. Pathogenesis of this association is not known but current hypothesis are based on either a decrease in the activity of hepatic glucuronyl transferase or an increase in the activity of intestinal glucuronidase. Correction of dehydration and alkalosis does not modify the hyperbilirubinemia which only disappears after pyloromiotomy.
摘要
本文描述了6例患有先天性肥厚性幽门狭窄并伴有黄疸的婴儿的临床和生物学表现。这种关联的发病机制尚不清楚，但目前的假说是基于肝葡萄糖醛酸转移酶活性降低或肠道葡萄糖醛酸酶活性增加。纠正脱水和碱中毒并不能改善高胆红素血症，高胆红素血症仅在幽门肌切开术后才消失。
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