Johnson R H, Lutwick L I, Huntley G A, Vosti K L
Ann Intern Med. 1976 Nov;85(5):587-92. doi: 10.7326/0003-4819-85-5-587.
Although disease caused by Arizona hinshawii is known to resemble the spectrum of clinical syndromes seen with Salmonella infections, little is known of their sensitivity to antimicrobials. We present three cases that are illustrative of Arizona sepsis, localized infection, or both; review the literature; and report sensitivities to 12 antimicrobials for 32 human and animal isolates of Arizona hinshawii from various geographic areas. With the exception of erythromycin and streptomycin, most strains were sensitive to many of the commonly used antibiotics. As with Salmonella infections, ampicillin or chloramphenicol appear to be the initial antimicrobial agents of choice for severe infections with A. hinshawii. Definitive antimicrobial therapy must be individualized on the basis of sensitivity testing and with regard to host factors.
虽然已知欣肖亚利桑那菌引起的疾病类似于沙门氏菌感染所呈现的一系列临床综合征，但对它们对抗菌药物的敏感性却知之甚少。我们呈现三例说明亚利桑那菌败血症、局部感染或两者皆有的病例；回顾文献；并报告来自不同地理区域的32株人源和动物源欣肖亚利桑那菌对12种抗菌药物的敏感性。除红霉素和链霉素外，大多数菌株对许多常用抗生素敏感。与沙门氏菌感染一样，氨苄西林或氯霉素似乎是治疗欣肖亚利桑那菌严重感染的首选初始抗菌药物。确切的抗菌治疗必须根据敏感性测试并考虑宿主因素进行个体化。
