Low P A
Mayo Medical School, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Curr Opin Neurol. 1998 Oct;11(5):531-7. doi: 10.1097/00019052-199810000-00016.
A limited autonomic neuropathy may underlie some unusual clinical syndromes, including the postural tachycardia syndrome, pseudo-obstruction syndrome, heat intolerance, and perhaps chronic fatigue syndrome. Antibodies to autonomic structures are common in diabetes, but their specificity is unknown. The presence of autonomic failure worsens prognosis in the diabetic state. Some autonomic neuropathies are treatable. Familial amyloid polyneuropathy may respond to liver transplantation. There are anecdotal reports of acute panautonomic neuropathy responding to intravenous gamma globulin. Orthostatic hypotension may respond to erythropoietin or midodrine.
局限性自主神经病变可能是某些特殊临床综合征的潜在病因，包括体位性心动过速综合征、假性肠梗阻综合征、不耐热，或许还包括慢性疲劳综合征。自主神经结构抗体在糖尿病患者中很常见，但其特异性尚不清楚。自主神经功能衰竭的存在会使糖尿病状态下的预后恶化。一些自主神经病变是可治疗的。家族性淀粉样多神经病可能对肝移植有反应。有急性泛自主神经病变对静脉注射丙种球蛋白有反应的个案报道。体位性低血压可能对促红细胞生成素或米多君有反应。
