Metelitsyna I P
Filatov Research Institute of Eye Diseases and Tissue Therapy, Academy of Medical Sciences of Ukraine, Odessa.
Ukr Biokhim Zh (1978). 1998 Mar-Apr;70(2):110-5.
The results of metabolic parameters determination, which characterize the state of protein's metabolism, membranes stability, cell s system of antioxidant deficiency at the patients with senile cataract are presented with the purpose to make clear the differences between biochemical mechanisms of lenses clouding progress at the elderly persons without and on the background of different somatic pathology. Our results have shown that disturbances of membranes structural-functional parameters and the lowering of activity glutathione metabolic system is more expressed at the patients with accompanying diseases of cardio-vascular system, gastro-intestinal tract, liver and chronic alcohol intoxication. The exhaustion of antioxidant system is observed at the patients with senile cataract in the cases of accompanying disease of liver and chronic alcohol intoxication unlike the patients without accompanying somatic diseases. Diseases of cardio-vascular's system, gastrointestinal tract and liver effort the metabolic disturbances in blood of the patients with senile cataract.