9-氧代-13（顺式和反式）-前列腺烯酸中碳18和碳19的微生物羟基化作用
Microbiological hydroxylation of carbons 18 and 19 in 9-oxo-13(cis and trans)-prostenoic acids.
作者信息
Lanzilotta R P, Bradley D G, McDonald K M, Tökés L
出版信息
Appl Environ Microbiol. 1976 Nov;32(5):726-8. doi: 10.1128/aem.32.5.726-728.1976.
Abstract
dl-9-Oxo-13 (cis and trans)-prostenoic acids were converted in high yields into their 18- and 19-hydroxy derivatives by cultures of Microascus trigonosporus. The structure elucidation of the microbial products is described.
摘要
通过三角孢小囊菌培养物，dl-9-氧代-13（顺式和反式）-前列腺酸能高产率地转化为它们的18-和19-羟基衍生物。文中描述了这些微生物产物的结构解析。
相似文献
1
Microbiological hydroxylation of carbons 18 and 19 in 9-oxo-13(cis and trans)-prostenoic acids.9-氧代-13（顺式和反式）-前列腺烯酸中碳18和碳19的微生物羟基化作用
Appl Environ Microbiol. 1976 Nov;32(5):726-8. doi: 10.1128/aem.32.5.726-728.1976.
2
The mechanism of experimental adipocere formation: substrate specificity on microbial production of hydroxy and oxo fatty acids.实验性尸蜡形成的机制：微生物产生羟基和氧代脂肪酸的底物特异性。
Forensic Sci Int. 1987 Dec;35(4):277-81. doi: 10.1016/0379-0738(87)90099-5.
3
Prostaglandins and congeners. V. (1) Synthesis of dl-prostaglandin E1, dl-11-deoxyprostaglandin E1, and dl-15-hydroxy-9-oxo-13-cis-prostenoic acid via conjugate addition of 3-trityloxy -1-octenylmagnesium bromides.前列腺素及其类似物。V.（1）通过3-三苯甲氧基-1-辛烯基溴化镁的共轭加成合成dl-前列腺素E1、dl-11-脱氧前列腺素E1和dl-15-羟基-9-氧代-13-顺式前列腺烯酸。
Prostaglandins. 1973 Apr;3(4):505-8. doi: 10.1016/0090-6980(73)90159-7.
4
Aureobasidium pullulans metabolism of prostaglandins of the A-type.出芽短梗霉对A类前列腺素的代谢
Prostaglandins. 1979 Jan;17(1):19-37. doi: 10.1016/0090-6980(79)90072-8.
5
Production of 3R-hydroxy-polyenoic fatty acids by the yeast Dipodascopsis uninucleata.单核双足囊酵母产生3R-羟基多烯脂肪酸
Lipids. 1997 Dec;32(12):1277-83. doi: 10.1007/s11745-006-0164-3.
6
Substrate specificity of Stenotrophomonas nitritireducens in the hydroxylation of unsaturated fatty acid.嗜麦芽窄食单胞菌在不饱和脂肪酸羟基化反应中的底物特异性。
Appl Microbiol Biotechnol. 2008 Feb;78(1):157-63. doi: 10.1007/s00253-007-1280-6. Epub 2007 Dec 1.
7
Bisallylic hydroxylation and epoxidation of polyunsaturated fatty acids by cytochrome P450.细胞色素P450对多不饱和脂肪酸的双烯丙基羟基化和环氧化作用
Lipids. 1996 Oct;31(10):1003-21. doi: 10.1007/BF02522457.
8
Microbial reduction of 1,3-dioxo-2-methyl-2-(3'0oxo-6'-carbomethoxyhexyl)-cyclopentane to form 1 beta-hydroxy-3-oxo-2beta-methyl-2alpha-(3'-oxo-6'-carbomethoxyhexyl)-cyclopentane, an intermediate for steroid total syntheses.微生物将1,3 - 二氧代 - 2 - 甲基 - 2 - (3'-氧代 - 6'-甲氧羰基己基) - 环戊烷还原，生成1β - 羟基 - 3 - 氧代 - 2β - 甲基 - 2α - (3'-氧代 - 6'-甲氧羰基己基) - 环戊烷，这是甾体全合成的一种中间体。
Appl Microbiol. 1975 Mar;29(3):427-9. doi: 10.1128/am.29.3.427-429.1975.
9
Determination of double bond positions in fatty acids with conjugated double bonds.
Biomed Mass Spectrom. 1978 Jul;5(7):439-443. doi: 10.1002/bms.1200050704.
10
Strobilurins F, G and H, three new antifungal metabolites from Bolinea lutea. II. Structure determination.来自黄褐绒盖牛肝菌的三种新型抗真菌代谢产物——嗜球果伞素F、G和H。II. 结构测定。
J Antibiot (Tokyo). 1990 Jun;43(6):661-7. doi: 10.7164/antibiotics.43.661.
本文引用的文献
1
A general biochemical synthesis of oxygenated prostaglandins E.含氧前列腺素E的一般生化合成
J Am Chem Soc. 1969 Jun 18;91(13):3685-7. doi: 10.1021/ja01041a065.
2
Synthesis of ( )-prostaglandin E 1 , ( )-11-deoxyprostaglandins E 1 , F 1 , and F 1 , and ( )-9-oxo-13-cis-prostenoic acid by conjugate addition of vinylcopper reagents.通过乙烯基铜试剂的共轭加成合成（）-前列腺素E1、（）-11-脱氧前列腺素E1、F1和F1以及（）-9-氧代-13-顺式前列腺酸。
J Am Chem Soc. 1972 Nov 1;94(22):7823-7. doi: 10.1021/ja00777a026.
3
19-Hydroxylated E prostaglandins as the major prostaglandins of human semen.19-羟基化E型前列腺素作为人类精液中的主要前列腺素。
Nature. 1974 Aug 23;250(5468):665-7. doi: 10.1038/250665a0.
4
Prostaglandins. VI. Correlation of the absolute configuration of pyrethrolone with that of the prostaglandins.前列腺素。VI. 除虫菊醇酮的绝对构型与前列腺素绝对构型的相关性。
J Am Chem Soc. 1973 Apr 18;95(8):2664-9. doi: 10.1021/ja00789a042.
5
The occurrence of 19-hydroxy F prostaglandins in human semen.19-羟基F前列腺素在人类精液中的存在情况。
FEBS Lett. 1975 Sep 1;57(1):22-5. doi: 10.1016/0014-5793(75)80143-8.
6
Prostaglandins in human seminal fluid: two novel compounds.人精液中的前列腺素：两种新化合物。
Science. 1975 Mar 21;187(4181):1093-4. doi: 10.1126/science.1114338.
7
19-Hydroxyprostaglandin E1 as a major component of the semen of primates.19-羟基前列腺素E1作为灵长类动物精液的主要成分。
Nature. 1976 Apr 8;260(5551):544-5. doi: 10.1038/260544a0.
Zotero 插件