Wang K C, Liang D C, Su T H, Hung F Y, Yang Y C
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan, R.O.C.
Changgeng Yi Xue Za Zhi. 1998 Sep;21(3):312-7.
Endometrial stromal sarcomas occur primarily in perimenopausal women and are quite uncommon in children. We report a case of high-grade endometrial stromal sarcoma in a 10-year-old girl, who initially experienced lower abdominal pain on voiding. After a series of examinations, surgical treatment was performed, including an extended total hysterectomy with bilateral salpingo-oophorectomy, bilateral pelvic lymph node sampling, and partial omentectomy. Adjuvant radiotherapy and hormonal therapy followed, however, the abdominal tumor recurred 9 months later. Invasion of the right lobe of the liver with compression of the inferior vena cava and pleural effusion was noted. The patient then received prolonged oral etoposide therapy. The treatment stabilized the tumor size and relieved her symptoms for 4 months. She finally succumbed to the disease as a result of distant metastasis.
子宫内膜间质肉瘤主要发生在围绝经期女性中，在儿童中相当罕见。我们报告一例10岁女孩的高级别子宫内膜间质肉瘤病例，该女孩最初排尿时出现下腹痛。经过一系列检查后，进行了手术治疗，包括扩大的全子宫切除术加双侧输卵管卵巢切除术、双侧盆腔淋巴结取样和部分大网膜切除术。随后进行了辅助放疗和激素治疗，然而，腹部肿瘤在9个月后复发。发现肝脏右叶受侵，下腔静脉受压并伴有胸腔积液。该患者随后接受了长时间的口服依托泊苷治疗。治疗使肿瘤大小稳定，并使她的症状缓解了4个月。她最终因远处转移而死于该疾病。
