Olson T L, Downey V W
Anesthesia Associates, Fargo, ND, USA.
Pediatr Nurs. 1998 Jul-Aug;24(4):385-9.
To compare the efficacy of dorsal penile nerve block (DPNB) and eutectic mixture of local anesthetic (EMLA) for attenuation of neonatal pain during circumcision.
A total of 20 infants born at a United States upper Midwestern hospital were involved in the study. Measurements of blood pressure, heart rate, respiratory rate, and oxygen saturation were obtained along with a Neonatal Infant Pain Scale (NIPS) grading at five separate intervals (baseline, restraint, incision, Gomco clamp application, and post circumcision) throughout the circumcision procedure. A comparison was done between the two groups regarding response to the noxious stimuli.
Infants demonstrate physiological and behavioral response to pain. These physiological and behavioral responses are observable and measurable. In addition, results show less response with the DPNB as compared to the EMLA.
There is a trend toward better pain control with the DPNB as compared to EMLA.
比较阴茎背神经阻滞(DPNB)和复方利多卡因乳膏(EMLA)在包皮环切术中减轻新生儿疼痛的疗效。
共有20名在美国中西部一家医院出生的婴儿参与了该研究。在整个包皮环切术过程中的五个不同时间点(基线、约束、切口、应用Gomco夹和包皮环切术后)测量血压、心率、呼吸频率和血氧饱和度,并进行新生儿疼痛量表(NIPS)评分。对两组对有害刺激的反应进行了比较。
婴儿对疼痛表现出生理和行为反应。这些生理和行为反应是可观察和可测量的。此外,结果显示与EMLA相比,DPNB的反应较小。
与EMLA相比,DPNB有更好地控制疼痛的趋势。