Yu S C, Lau W Y, Leung W T, Liew C T, Leung N W, Metreweli C
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
Br J Radiol. 1998 Jun;71(846):621-4. doi: 10.1259/bjr.71.846.9849384.
This study evaluates the efficacy of ultrasound guided percutaneous biopsy using an 18 gauge automated side-cutting needle in the diagnosis of small (< or = 3 cm) focal hepatic lesions. 137 consecutive percutaneous biopsies of 131 different small (< or = 3 cm) focal hepatic lesions were included. 11 biopsies were performed on lesions of < or = 1 cm in diameter, 56 were on lesions 1.1-2 cm in size and 70 on lesions 2.1-3 cm in size (average 2.3 +/- 0.7 cm; median 2.3 cm; range 0.7-3 cm). The biopsy specimen was sufficient for diagnosis in 135 cases (98.5%). The sensitivity for diagnosing malignancy was 96.4%; specificity was 100%, positive and negative predictive values were 100% and 94.6%, respectively; accuracy was 97.8%. There was no statistically significant difference in the diagnostic efficacy for lesions of different pathology and size. No significant post-biopsy complication occurred. It is concluded that the 18 gauge Temno needle is safe and effective in diagnosing small hepatic lesions.
本研究评估了使用18G自动侧切针在超声引导下经皮穿刺活检诊断小（≤3cm）局灶性肝病变的疗效。纳入了对131个不同的小（≤3cm）局灶性肝病变进行的137次连续经皮穿刺活检。对直径≤1cm的病变进行了11次活检，对大小为1.1 - 2cm的病变进行了56次活检，对大小为2.1 - 3cm的病变进行了70次活检（平均2.3±0.7cm；中位数2.3cm；范围0.7 - 3cm）。135例（98.5%）的活检标本足以用于诊断。诊断恶性肿瘤的敏感性为96.4%；特异性为100%，阳性和阴性预测值分别为100%和94.6%；准确性为97.8%。不同病理和大小的病变在诊断效能上无统计学显著差异。活检后未发生明显并发症。结论是，18G Temno针在诊断小肝病变方面安全有效。
