Dubuisson J B
Presse Med. 1998 Nov 14;27(35):1793-4.
In vitro fertilization (IVF) has revolutionalized management strategies proposed for infertility to the point where some have suggested that tubal surgery is no longer indicated. The objective being to obtain the largest number of viable births at minimum cost and maximum patient comfort, we strongly believe that tubal surgery and IVF are complementary tools for patients with tubal infertility. The choice depends on the severity and the localization of the lesions. For example, in patients with hydrosalpinx (the most frequent tubal lesion) and healthy or moderately altered mucosa, the rate of in utero pregnancies after tubal plasty by laparoscopic salpingostomy (53% in our series) is quite comparable with the rate after IVF. In this large group, tubal surgery should be proposed first. Tubal surgery may also be indicated in other less frequent lesions such as proximal obstructions where we have obtained excellent results (56% live births within 2 years of surgery). Of course, the final decision is made by the couple, well informed of the advantages and disadvantages of each technique. Performed by a well-trained team with extensive experience in reproduction, tubal surgery, particularly with the development of micro-instruments for laparoscopy, remains a treatment of choice for patients with tubal infertility.
体外受精(IVF)彻底改变了针对不孕症提出的治疗策略,以至于有人认为输卵管手术已不再适用。目标是以最低成本和最大程度的患者舒适度获得最多的活产,我们坚信输卵管手术和体外受精是输卵管性不孕症患者的互补工具。选择取决于病变的严重程度和部位。例如,对于输卵管积水(最常见的输卵管病变)且黏膜健康或轻度改变的患者,腹腔镜输卵管造口术进行输卵管成形术后的宫内妊娠率(我们系列研究中的比例为53%)与体外受精后的妊娠率相当。在这一庞大群体中,应首先建议进行输卵管手术。输卵管手术也可用于其他不太常见的病变,如近端梗阻,我们在这方面取得了优异的结果(术后2年内活产率为56%)。当然,最终的决定由夫妇做出,他们充分了解每种技术的优缺点。由训练有素、在生殖领域有丰富经验的团队进行,输卵管手术,特别是随着腹腔镜显微器械的发展,仍然是输卵管性不孕症患者的首选治疗方法。