Pedersen F M, Lassen A T, de Muckadell O B
Department of Medical Gastroenterology S, Odense University Hospital.
Dan Med Bull. 1998 Nov;45(5):533-5.
Most follow-up studies of patients with common bile duct stones treated with endoscopic sphincterotomy include older patients. Therefore, the aim of the present study was to do a medium-term follow-up of patients under the age of 60 years, who underwent endoscopic sphincterotomy and removal of common bile duct stones.
Eighty-six (68 women) consecutive patients less than 60 years of age (median age 47 years) were evaluated. The median observation time after endoscopic sphincterotomy was 27.1 months. Complete follow-up was accomplished in 80 patients.
Twenty-five patients had undergone cholecystectomy prior to the endoscopic sphincterotomy. Sixty-one patients were discharged after endoscopic sphincterotomy with gallbladder left in situ. Cholecystectomy was not needed in 27 patients, of whom 23 had gallbladder stones. In 13 of 61 patients subsequent elective cholecystectomy was planned at the time of endoscopic sphincterotomy. Recurrent attacks of biliary colic required elective cholecystectomy in another thirteen patients. Acute cholecystectomy was undertaken in eight patients due to acute cholecystitis (n = 4) or biliary colic (n = 4). Seven of eight acute cholecystectomies were performed within 152 days after the endoscopic sphincterotomy. The overall median time until cholecystectomy was 51 days (25-75 percentiles, 23-103 days).
One third of the patients had been cholecystectomized prior to the endoscopic treatment of their common bile duct stones. Nearly half of the young patients discharged after endoscopic sphincterotomy for common bile duct stones with the gallbladder left in situ at the time of endoscopic sphincterotomy managed well without any need for cholecystectomy.
大多数接受内镜括约肌切开术治疗胆总管结石患者的随访研究纳入的是老年患者。因此,本研究的目的是对年龄在60岁以下接受内镜括约肌切开术及胆总管结石取出术的患者进行中期随访。
对86例(68例女性)年龄小于60岁(中位年龄47岁)的连续患者进行评估。内镜括约肌切开术后的中位观察时间为27.1个月。80例患者完成了完整随访。
25例患者在内镜括约肌切开术前已行胆囊切除术。61例患者在内镜括约肌切开术后出院时胆囊保留原位。27例患者无需行胆囊切除术,其中23例有胆囊结石。61例患者中有13例在内镜括约肌切开术时计划后续择期胆囊切除术。另有13例患者因胆绞痛反复发作需要择期胆囊切除术。8例患者因急性胆囊炎(4例)或胆绞痛(4例)行急诊胆囊切除术。8例急诊胆囊切除术中7例在接受内镜括约肌切开术后152天内进行。至胆囊切除的总体中位时间为51天(四分位数间距,23 - 103天)。
三分之一的患者在接受内镜治疗胆总管结石前已行胆囊切除术。在内镜括约肌切开术时胆囊保留原位的胆总管结石患者中,近一半的年轻患者术后恢复良好,无需行胆囊切除术。