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[动物冷却后垂体前叶超微结构的变化]

[Changes in the ultrastructure of the anterior lobe of the pituitary after subjecting animals to cooling].

作者信息

Monastyrskaia B I, Teshchenko G A

出版信息

Arkh Anat Gistol Embriol. 1976 Sep;71(9):54-8.

PMID:985108
Abstract

Stress reactions caused by extreme factors have a common nonspecific main component-a release of ACTH into the blood stream and increased functional activity of corticotropic cells of the anterior lobe of the hypophysis. Qualitative properties of the acting agents depending on their nature determine other adaptive changes of hormonal and metabolic processes in the organism after the interference. The study of the dynamics of the ultrastructure of glandular cells of the rat's hypophysis anterior lobe after a single severe cooling has revealed a sharply pronounced early mobilization of thyreotrops. The increased thyreotropic activity is an additional specific component of stressor reaction which is caused by cooling. The electron microscopic study of the structure and topography of glandular elements has revealed a cycle of functional-morphological changes completed within a day after the exposure.

摘要

极端因素引起的应激反应有一个共同的非特异性主要成分——促肾上腺皮质激素释放到血流中,以及垂体前叶促肾上腺皮质激素细胞的功能活动增强。作用因子的性质决定了干扰后机体激素和代谢过程的其他适应性变化。对大鼠垂体前叶腺细胞在单次严重冷却后的超微结构动态研究表明,促甲状腺激素细胞有明显的早期动员。促甲状腺活性增加是冷却引起的应激反应的一个额外的特定成分。对腺性成分的结构和布局进行的电子显微镜研究揭示了暴露后一天内完成的功能-形态变化周期。

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