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医院获得性伤口感染:一项患病率研究及危险因素分析

Nosocomial wound infections: a prevalence study and analysis of risk factors.

作者信息

Wischnewski N, Kampf G, Gastmeier P, Schlingmann J, Schumacher M, Daschner F, Ruden H

机构信息

Institute of Hygiene, Environmental and Occupational Medicine, Free University of Berlin, Germany.

出版信息

Int Surg. 1998 Apr-Jun;83(2):93-7.

PMID:9851321
Abstract

This first German prevalence study surveilling nosocomial wound infections (NWI) was carried out in 72 representatively selected hospitals. NWI were recorded by 4 validated investigators. Seventy-nine NWI were recorded among 4983 operated patients (prevalence rate: 1.61%), most of them after amputation of limbs (6.1%) and operations on the colon or rectum (3.1%). The 3 risk factors from the NNIS (National Nosocomial Infection Surveillance) index for postoperative wound infections were for the first time applied in this prevalence study. Patients with contaminated wounds had significantly more wound infections (P=0.01, likelihood ratio test) whereas, in contrast to the NNIS index, patients with ASA score >3 (P= 0.07) or long lasting operations (>75th percentile) did not (P=0.1). Therefore, for the stratification of NWI rates wound contamination is the single most important factor.

摘要

这项首个针对医院获得性伤口感染(NWI)的德国患病率研究在72家经代表性选取的医院开展。NWI由4名经验证的调查人员记录。在4983例手术患者中记录到79例NWI(患病率:1.61%),其中大多数发生在截肢术后(6.1%)以及结肠或直肠手术后(3.1%)。本患病率研究首次应用了来自美国国家医院感染监测系统(NNIS)指标中的3个术后伤口感染风险因素。伤口受污染的患者伤口感染明显更多(P = 0.01,似然比检验),然而,与NNIS指标不同的是,美国麻醉医师协会(ASA)评分>3的患者(P = 0.07)或手术时间长(>第75百分位数)的患者并未出现更多感染(P = 0.1)。因此,对于医院获得性伤口感染率的分层而言,伤口污染是唯一最重要的因素。

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