Semashko M I
Arkh Patol. 1976;38(8):32-40.
Post-mortem morphological, histochemical, and morphometric investigations of the adrenals in 46 deceased patients who suffered from meningococcemia with and without lesions of the meninges were carried out. The control group was composed of 7 practically healthy persons who had perished suddenly as a result of craniocerebral trauma. It was shown that the adrenals might often be seriously damaged in meningococcemia without clinical and morphological signs of meningitis. Hemodynamic disorders, in particular, involvement of the vessels of the microcirculatory bed, contributed considerably to the lesions of the adrenals. However, even in meningococcemia free from signs of meningitis, in a number of cases individual areas of the cortex retained a high functional activity. In meningococcemia combined with lesions of the meninges, despite considerable damage of the cortical layer, in the majority of cases there were evidences of the tense functioning of the adrenal cells.
对46例患有脑膜炎球菌血症且有或没有脑膜病变的死亡患者的肾上腺进行了尸检形态学、组织化学和形态计量学研究。对照组由7名因颅脑外伤突然死亡的实际健康者组成。结果表明，在没有脑膜炎临床和形态学体征的脑膜炎球菌血症中，肾上腺常常会受到严重损害。血流动力学紊乱，尤其是微循环床血管受累，对肾上腺病变有很大影响。然而，即使在没有脑膜炎体征的脑膜炎球菌血症中，在一些病例中皮质的个别区域仍保持着较高的功能活性。在合并脑膜病变的脑膜炎球菌血症中，尽管皮质层受到相当大的损害，但在大多数病例中仍有肾上腺细胞功能紧张的证据。
