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[肺部疾病的形态学及其在新生儿窒息发生发展中的作用]

[Morphology of pneumopathies and their role in the development of asphyxia neonatorum].

作者信息

Birkun A A, Oleĭnik A I

出版信息

Arkh Patol. 1976;38(8):40-6.

PMID:985137
Abstract

Histories of deliveries and development records of 44 newborns with penumopathies who had died on the first days of life in the presence of phenomena of the syndrome of respiratory disorder were analysed and the newborns' lungs were morphologically investigated. The investigation made it possible to single out the following forms of pneumopathy in newborns: edematous-hemorrhagic, hyaline, atelectatic, aspirated, and mixed. In the majority of cases the syndrome of respiratory disorder was a sequela of hypoxia of the intrauterine origin which continued during the first hours and days of life after birth. Such "primary asphyxia" may lead to the development of pneumopathy in a neonate. On the other hand, "secondary asphyxia" in many cases represent sequelae of penumopathy destructural and functional immaturity of the pulmonary tissue, hypoxia, a higher permeability of vessels of the microcirculatory bed, spasm of small pulmonary arteris contributed considerably to the development of penumopathies.

摘要

对44例患有肺部疾病且在出生后第一天因呼吸障碍综合征现象死亡的新生儿的分娩史和发育记录进行了分析,并对新生儿的肺部进行了形态学研究。该研究使得能够区分出新生儿肺部疾病的以下几种形式:水肿 - 出血性、透明膜性、肺不张性、吸入性和混合性。在大多数情况下,呼吸障碍综合征是宫内缺氧的后遗症,在出生后的最初几个小时和几天内仍持续存在。这种“原发性窒息”可能导致新生儿肺部疾病的发展。另一方面,“继发性窒息”在许多情况下是肺部疾病的后遗症,肺组织的结构和功能不成熟、缺氧、微循环床血管通透性增加、小肺动脉痉挛在很大程度上促成了肺部疾病的发展。

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