Dorokhov I I, Ivanova I A
Arkh Patol. 1976;38(8):71-3.
A case of cryptococcosis of the brain in a male patient 47 years of age is described. Duration of the disease--about one year. Clincally it was accompanied by epileptic seizures with loss of consciousness. Diagnosis of cryptococcosis was made following the histological investigation of a part of the brain removed in connection with tumour. Morphologically, there was detected an area of necrosis and aggregation of yeast-like fungi with the typical of cryptococcus oval form and felatinous capsule showing intensive colouration when stained by Hochkiss' method. The pathogenic agent was detected in the spinal fluid of the patient and in the tissue culture.
描述了一例47岁男性患者的脑隐球菌病。病程约一年。临床上伴有癫痫发作和意识丧失。在对因肿瘤切除的部分脑组织进行组织学检查后，做出了隐球菌病的诊断。在形态学上，检测到一个坏死区域以及酵母样真菌的聚集，这些真菌具有隐球菌典型的椭圆形形态和胶状荚膜，用霍奇基斯方法染色时显示出强烈的着色。在患者的脑脊液和组织培养物中检测到了病原体。
