Lydiard R B
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425, USA.
J Affect Disord. 1998 Sep;50 Suppl 1:S35-9. doi: 10.1016/s0165-0327(98)00090-1.
Social phobia is a potentially disabling condition requiring effective and well tolerated treatment. The monoamine oxidase inhibitors, benzodiazepines and, more recently, the selective serotonin reuptake inhibitors (SSRIs) have all shown promise as treatments for this disorder. Paroxetine, the most thoroughly studied SSRI, has been shown to be effective in treating the symptoms of generalized social phobia in a large-scale, placebo-controlled trial. Paroxetine and the other SSRIs show promise as a new and safe therapeutic choice for patients with social phobia.
社交恐惧症是一种可能导致功能障碍的疾病,需要有效且耐受性良好的治疗。单胺氧化酶抑制剂、苯二氮卓类药物,以及最近的选择性5-羟色胺再摄取抑制剂(SSRI)都显示出有望成为治疗这种疾病的方法。帕罗西汀是研究最充分的SSRI,在一项大规模、安慰剂对照试验中已证明其对治疗广泛性社交恐惧症的症状有效。帕罗西汀和其他SSRI显示出有望成为社交恐惧症患者一种新的安全治疗选择。