Muhr O, Stockhusen H, Müller O
Arch Orthop Unfallchir. 1976 Oct 8;86(1):115-28. doi: 10.1007/BF00415309.
Uncemented fixation and low-fraction materials are the basis of this experiment. Plastics with an elasticity similar to the bone ("isoelasticity") show very propitious material qualities. The direct cementless incorporation of test bodies must be checked. In 63 sheep isoelastic total hip joints were implanted. After 2 till 51 weeks the animals were sacrificed and 44 specimen of hips and organs were explored macroscopically, radiologically, spherimetrically and histologically. The result was: 1. Plastic hip prosthesis are incorporated in the bone, but the boundary layer is built by a collagenous fiber tissue. 2. Loosening brings resoption of the bone and expansion of the structural changed soft tissue. 3. The transformation of the femoral cortex to osteoporosis is considered possibly as the consequence of an insufficient biological transfer of the weight. 4. Fractures of the femoral prosthesis-stem could not be observed. 5. The radiology allows at the pelvis prosthesis a concret statement concerning stability, on the femoral part a probable one. 6. The abrasion is minimal, the tissue reaction to abrasion products is unessential. 7. Small abrasion particles are carried of by the lymph tract and stored in the first regional gland. A more distant spreading is not demonstrable.
非骨水泥固定和低摩擦材料是本实验的基础。具有与骨骼相似弹性(“等弹性”)的塑料显示出非常有利的材料特性。必须检查测试体的直接非骨水泥植入情况。在63只绵羊身上植入了等弹性全髋关节。2至51周后处死动物,对44个髋关节和器官标本进行了宏观、放射学、球面测量和组织学检查。结果如下:1. 塑料髋关节假体被骨组织包埋,但边界层由胶原纤维组织构成。2. 假体松动导致骨质吸收和结构改变的软组织扩张。3. 股骨皮质向骨质疏松的转变可能被认为是重量生物传递不足的结果。4. 未观察到股骨假体柄骨折。5. 放射学检查对于骨盆假体的稳定性能给出确切结论,对于股骨部分则能给出可能的结论。6. 磨损极小,组织对磨损产物的反应不明显。7. 小的磨损颗粒通过淋巴道被带走并储存在第一区域淋巴结中,未发现更远距离的扩散。