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细胞黏附的调节,必需脂肪酸抗癌作用的核心机制(综述)。

Regulation of cell adhesion, a central mechanism in the anticancer action of essential fatty acids (review).

作者信息

Jiang W G

机构信息

Metastasis Research Group, University Department of Surgery, University of Wales College of Medicine, Cardiff, UK.

出版信息

Int J Mol Med. 1998 Mar;1(3):621-5. doi: 10.3892/ijmm.1.3.621.

Abstract

Certain members of essential fatty acids (EFAs) are known to have anticancer functions. It has been established in recent years that some of these anticancer actions are via the effects of these fatty acids on the adhesive properties of cancer cells, including cell-cell and cell-matrix adhesions. These discoveries have implicated EFAs as a group of novel agents, able to regulate adhesive function of cancer cells and thus bearing clinical importance.

摘要

已知必需脂肪酸(EFA)的某些成分具有抗癌功能。近年来已经证实,其中一些抗癌作用是通过这些脂肪酸对癌细胞黏附特性的影响来实现的,包括细胞间黏附和细胞与基质的黏附。这些发现表明必需脂肪酸是一类新型药物,能够调节癌细胞的黏附功能,因此具有临床重要性。

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