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老年人冠状动脉搭桥手术的结果

Outcomes of coronary artery bypass surgery in elderly people.

作者信息

MacDonald P, Stadnyk K, Cossett J, Klassen G, Johnstone D, Rockwood K

机构信息

Division of Cardiology, Dalhousie University, Halifax, Nova Scotia.

出版信息

Can J Cardiol. 1998 Oct;14(10):1215-22.

PMID:9852935
Abstract

OBJECTIVES

To document the impact of coronary artery bypass (CABG) surgery on quality of life in elderly people three months after surgery; to compare quality of life measures; to examine predictors of poor quality of life; and to assess the predictive validity of global clinical rating scales.

STUDY DESIGN

Prospective cohort study with postoperative, three-month and one-year follow-up.

SETTING

A 700-bed tertiary care teaching hospital in Halifax, Nova Scotia.

PATIENTS

One hundred of 200 consecutive patients, 75 years and older, undergoing CABG.

MEASURES

Demographic information, clinical data and global clinical ratings were collected at baseline to assess risk for adverse outcome (death, stroke, functional impairment) at each follow-up. Quality of life three months post-CABG was documented using the RAND 36-Item Health Survey and the Seattle Angina Questionnaire.

MAIN RESULTS

Perioperative deaths occurred in four patients, disabling strokes in six and postoperative complications in seven. Three additional deaths occurred by the three-month follow-up and nine more by one year. On average, important improvements in quality of life were observed at three months' follow-up, using both assessments of quality of life.

CONCLUSIONS

Many elderly patients do well after CABG surgery, but a higher proportion than is seen in younger patients have complications leading to death and disability. A global clinical measure by the attending cardiologist at baseline did not identify patients at a higher risk. Follow-up studies are needed to assess long term outcomes of older patients at higher risk of death or a poor quality of life after CABG surgery.

摘要

目的

记录冠状动脉搭桥术(CABG)对老年患者术后三个月生活质量的影响;比较生活质量测量指标;检查生活质量差的预测因素;并评估整体临床评定量表的预测效度。

研究设计

前瞻性队列研究,术后进行三个月和一年的随访。

研究地点

新斯科舍省哈利法克斯市一家拥有700张床位的三级护理教学医院。

患者

200例连续接受CABG手术的75岁及以上患者中的100例。

测量指标

在基线时收集人口统计学信息、临床数据和整体临床评定,以评估每次随访时不良结局(死亡、中风、功能障碍)的风险。使用兰德36项健康调查和西雅图心绞痛问卷记录CABG术后三个月的生活质量。

主要结果

围手术期有4例患者死亡,6例发生致残性中风,7例出现术后并发症。到三个月随访时又有3例死亡,到一年时又有9例死亡。使用两种生活质量评估方法,均观察到在三个月随访时生活质量有显著改善。

结论

许多老年患者CABG手术后恢复良好,但与年轻患者相比,有更高比例的患者出现导致死亡和残疾的并发症。主治心脏病专家在基线时进行的整体临床测量未能识别出风险较高的患者。需要进行随访研究以评估CABG手术后死亡风险较高或生活质量较差的老年患者的长期结局。

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