Myung S J, Yang S K, Jung H Y, Jung S A, Kang G H, Ha H K, Hong W S, Min Y I
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
J Gastroenterol. 1998 Dec;33(6):876-9. doi: 10.1007/s005350050192.
We report a case of Crohn's disease with low serum zinc concentration in a 26-year-old woman. She demonstrated acrodermatitis enteropathica and decreased visual acuity during total parenteral nutrition. Subsequent intravenous zinc supplementation resulted in alleviation of the skin lesions and improvement of visual acuity. This case supports the notion that depressed serum zinc in Crohn's disease may cause clinical manifestations, such as acrodermatitis enteropathica and retinal dysfunction, which may be correctable with zinc supplementation.
我们报告了一例26岁女性克罗恩病患者血清锌浓度偏低的病例。她在全胃肠外营养期间出现了肠病性肢端皮炎和视力下降。随后静脉补充锌导致皮肤病变减轻和视力改善。该病例支持这样一种观点，即克罗恩病患者血清锌降低可能会导致临床表现，如肠病性肢端皮炎和视网膜功能障碍，而补充锌可能会纠正这些表现。
