大鼠腹外侧膝状体内含一氧化氮合酶的神经元投射至视前顶盖核。

Nitric oxide synthase containing neurons in the ventral lateral geniculate of the rat project to the optic pretectal nuclei.

作者信息

Meng X W, Ohara P T, Ralston H J

机构信息

Department of Anatomy and W.M. Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco 94143-0452, USA.

出版信息

Neurosci Lett. 1998 Nov 6;256(2):89-92. doi: 10.1016/s0304-3940(98)00771-x.

DOI:10.1016/s0304-3940(98)00771-x

PMID:9853710

Abstract

We combined fluorescent tracing with immunohistochemistry to examine nitric oxide synthase (NOS) containing neurons in the rat ventral lateral geniculate nucleus (vLGN). NOS immunopositive neurons in vLGN had a similar appearance to previously described NADPH-d positive neurons. The majority (96%) of the NOS immunopositive neurons in vLGN projected to the pretectal nuclei and these represented 16% of all the vLGN neurons that project to the pretectal nuclei. No NOS immunopositive neurons projected to the superior colliculus. Co-localization of NADPH-d and gamma-aminobutyric acid (GABA) has been reported in vLGN neurons but we found few cells containing both NOS and GABA.

摘要

我们将荧光追踪与免疫组织化学相结合，以检查大鼠腹侧外侧膝状核（vLGN）中含一氧化氮合酶（NOS）的神经元。vLGN中NOS免疫阳性神经元的外观与先前描述的NADPH-d阳性神经元相似。vLGN中大多数（96%）NOS免疫阳性神经元投射到顶盖前核，这些神经元占投射到顶盖前核的所有vLGN神经元的16%。没有NOS免疫阳性神经元投射到上丘。已有报道称vLGN神经元中存在NADPH-d和γ-氨基丁酸（GABA）的共定位，但我们发现同时含有NOS和GABA的细胞很少。