Gbadoé A D, Messie K, Atakouma D Y, Vovor A, Tatagan-Agbi K, Késsié K, Vilmer E, Assimadi J K
Service de pédiatrie, CHU de Lomé-Tokoin, Togo.
Sante. 1998 Sep-Oct;8(5):337-41.
Idiopathic thrombocytopenic purpurea (ITP) is an autoimmune disease that occurs frequently in Europe and the US, but has rarely been described in Africa. Case report. An 8-year-old girl was admitted for cutaneous and mucosal bleeding. She had a low platelet count (11 x 10(9)/l). ITP was suspected and the diagnosis was confirmed by bone marrow examination. Corticosteroid treatment was effective.
This is the second case reported in Togo since 1982. The diagnosis of the disease is straightforward, so the lack of cases reported in central Africa suggests that the disease is rare in this region. The rarity of the disease may be due to genetic or environmental factors, or it may simply be that physicians overlook this disease when making their diagnosis. Corticosteroids are now the preferred treatment for ITP because of the risk of transmitting Creutzfeldt-Jacob's disease by intravenous administration of immunoglobulin. Splenectomy is the ultimate treatment for chronic forms.
Unlike other diseases, the diagnosis and treatment of which require methods unavailable in parts of Africa, ITP treatment, as currently practiced in countries of the northern hemisphere, is within the reach of most African countries. Further studies are required to determine the true frequency of the disease in central Africa.
特发性血小板减少性紫癜（ITP）是一种自身免疫性疾病，在欧洲和美国频繁发生，但在非洲鲜有报道。病例报告。一名8岁女孩因皮肤和黏膜出血入院。她的血小板计数较低（11×10⁹/L）。怀疑为ITP，骨髓检查确诊。皮质类固醇治疗有效。
这是自1982年以来多哥报道的第二例病例。该疾病的诊断 straightforward，因此中非地区缺乏病例报告表明该疾病在该地区罕见。该疾病的罕见可能是由于遗传或环境因素，或者可能仅仅是医生在诊断时忽略了这种疾病。由于静脉注射免疫球蛋白有传播克雅氏病的风险，皮质类固醇现在是ITP的首选治疗方法。脾切除术是慢性形式的最终治疗方法。
与其他疾病不同，其诊断和治疗需要非洲部分地区无法获得的方法，而目前北半球国家所采用的ITP治疗方法，大多数非洲国家都可以做到。需要进一步研究以确定中非地区该疾病的真实发病率。
