Baldini E, Gugenheim J, Tran A, Spinelli R, Ouzan D, Saint-Paul M C, Fabiani P, Mouiel J
Service de Chirurgie Digestive, Vidéochirurgie et Transplantation Hépatique, Hôpital de L'Archet 2, Université de Nice, Sophia-Antipolis.
Gastroenterol Clin Biol. 1998 Oct;22(10):821-3.
Neuroendocrine tumors of the biliary tree are rare. In all cases except one, diagnosis was made in symptomatic patients. We report a case of an asymptomatic intrahepatic bile duct neuroendocrine tumor in a 74-year old man. To our knowledge, this is the second reported case of an asymptomatic intrahepatic bile duct neuroendocrine tumor. Diagnosis was only made by anatomopathological examination of the tumor after resection. Systemic and immunohistochemical hormonal screening was negative. Twenty months after surgery, the patient was asymptomatic and there was no recurrence.
胆管神经内分泌肿瘤较为罕见。除1例以外,所有病例均在出现症状的患者中得以诊断。我们报告1例74岁男性无症状肝内胆管神经内分泌肿瘤病例。据我们所知,这是第二例报告的无症状肝内胆管神经内分泌肿瘤病例。仅在肿瘤切除后通过解剖病理学检查才得以确诊。全身及免疫组化激素筛查均为阴性。术后20个月,患者无症状且无复发。