Mjahed K, Hammamouchi B, Hammoudi D, Harti A, Miguil M, Barrou L
CHU Ibn Rochd, Casablanca, Maroc.
J Gynecol Obstet Biol Reprod (Paris). 1998 Oct;27(6):607-10.
Study of hemostatic disorders during eclampsia, their risk factors, maternal complications and associated mortality.
Retrospective study concerning 106 cases of severe eclampsia treated in intensive care between September 1992 and December 96. Patients with or without hemostatic disorders were compared for laboratory findings, maternal complications and mortality.
Forty patients had hemostasis disorders as follows: isolated thrombopenia in 19 cases, disseminated intravascular coagulation (DIC) in 5 cases, Hellp syndrome associated to DIC in 7 cases and Hellp syndrome in 9 cases. Hemostasis disorders were associated to maternal advanced age, but not with gestational age or blood pressure in admission or time of convulsions. Complications and mortality associated with hemostasis disorders were more frequent compared to patients without hemostasis disorders. Among the 17 deaths of our series, 10 had hemostasis disorders.
Hemostasis disorders were prognosis factors in eclampsia requiring systematic laboratory tests at admission and immediate delivery.
研究子痫期间的止血障碍、其危险因素、孕产妇并发症及相关死亡率。
对1992年9月至1996年12月在重症监护室治疗的106例重度子痫患者进行回顾性研究。比较有或无止血障碍患者的实验室检查结果、孕产妇并发症及死亡率。
40例患者出现止血障碍，情况如下：单纯血小板减少19例，弥散性血管内凝血（DIC）5例，与DIC相关的HELLP综合征7例，HELLP综合征9例。止血障碍与孕产妇高龄有关，但与入院时的孕周、血压或抽搐时间无关。与无止血障碍的患者相比，与止血障碍相关的并发症和死亡率更为常见。在我们系列研究的17例死亡病例中，10例有止血障碍。
止血障碍是子痫的预后因素，需要在入院时进行系统的实验室检查并立即分娩。
