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怀孕和哺乳期小鼠的乳腺糖皮质激素受体

Mammary glucocorticoid receptor of mice in pregnancy and in lactation.

作者信息

Chomczynski P, Zwierzchowski L

出版信息

Biochem J. 1976 Aug 15;158(2):481-3. doi: 10.1042/bj1580481.

DOI:10.1042/bj1580481
PMID:985440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1163992/
Abstract

Activity of glucocorticoid receptor in mouse mammary cytosol changes during lactogenesis. The highest receptor activity is observed in the second half of pregnancy. The receptor from mammary glands from lactating and pregnant mice exhibits the same sedimentation pattern, as well as the same specificity and affinity for binding of steroid hormones.

摘要

在泌乳发生过程中，小鼠乳腺细胞质中糖皮质激素受体的活性会发生变化。在妊娠后半期观察到最高的受体活性。来自泌乳和妊娠小鼠乳腺的受体表现出相同的沉降模式，以及对类固醇激素结合的相同特异性和亲和力。

相似文献

1
Mammary glucocorticoid receptor of mice in pregnancy and in lactation.怀孕和哺乳期小鼠的乳腺糖皮质激素受体
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2
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Steroid derivatives for electrophilic affinity labelling of glucocorticoid binding sites: interaction with the glucocorticoid receptor and biological activity.用于糖皮质激素结合位点亲电亲和标记的类固醇衍生物：与糖皮质激素受体的相互作用及生物活性
J Steroid Biochem. 1983 Apr;18(4):375-82. doi: 10.1016/0022-4731(83)90054-7.

引用本文的文献

1
Introduction: secretory activation: from the past to the future.引言：分泌激活：从过去到未来。
J Mammary Gland Biol Neoplasia. 2007 Dec;12(4):205-10. doi: 10.1007/s10911-007-9060-6. Epub 2007 Nov 15.
2
The role of glucocorticoids in secretory activation and milk secretion, a historical perspective.糖皮质激素在分泌激活和乳汁分泌中的作用：历史视角
J Mammary Gland Biol Neoplasia. 2007 Dec;12(4):293-304. doi: 10.1007/s10911-007-9055-3. Epub 2007 Nov 14.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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Glucocorticoid receptors: relations between steroid binding and biological effects.糖皮质激素受体：类固醇结合与生物学效应之间的关系。
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