怀孕和哺乳期小鼠的乳腺糖皮质激素受体
Mammary glucocorticoid receptor of mice in pregnancy and in lactation.
作者信息
Chomczynski P, Zwierzchowski L
出版信息
Biochem J. 1976 Aug 15;158(2):481-3. doi: 10.1042/bj1580481.
Abstract
Activity of glucocorticoid receptor in mouse mammary cytosol changes during lactogenesis. The highest receptor activity is observed in the second half of pregnancy. The receptor from mammary glands from lactating and pregnant mice exhibits the same sedimentation pattern, as well as the same specificity and affinity for binding of steroid hormones.
摘要
在泌乳发生过程中，小鼠乳腺细胞质中糖皮质激素受体的活性会发生变化。在妊娠后半期观察到最高的受体活性。来自泌乳和妊娠小鼠乳腺的受体表现出相同的沉降模式，以及对类固醇激素结合的相同特异性和亲和力。
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