血清肝细胞生长因子水平与胃癌进展相关。
Serum hepatocyte growth factor level associate with gastric cancer progression.
作者信息
Wu C W, Chi C W, Su T L, Liu T Y, Lui W Y, P'eng F K
机构信息
Department of Surgery, Veterans General Hospital-Taipei, Taiwan, Republic of China.
出版信息
Anticancer Res. 1998 Sep-Oct;18(5B):3657-9.
We have measured serum HGF levels from 80 gastric cancer patients and 51 normal subjects by enzyme-linked immunosorbent assay. The results showed that the mean value of serum HGF level in gastric cancer patients was significantly higher than in normal subjects (0.30 +/- 0.02 vs 0.22 +/- 0.05 ng/ml; p = 0.005). The increase was stage related. Patients with serum HGF < or = 0.30 ng/ml survived longer than those with serum HGF > 0.30 ng/ml (p = 0.02). These data suggest that HGF involve in progression of gastric cancer.
我们通过酶联免疫吸附测定法测量了80例胃癌患者和51名正常受试者的血清肝细胞生长因子（HGF）水平。结果显示，胃癌患者血清HGF水平的平均值显著高于正常受试者（0.30±0.02 vs 0.22±0.05 ng/ml；p = 0.005）。这种升高与分期相关。血清HGF≤0.30 ng/ml的患者比血清HGF>0.30 ng/ml的患者存活时间更长（p = 0.02）。这些数据表明HGF参与了胃癌的进展。
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