Caruso M L, Rizzi E
Department of Histopathology, I.R.C.C.S. S. De Bellis, Bari, Italy.
Anticancer Res. 1998 Sep-Oct;18(5B):3781-3.
The detection of HP infection by means of non invasive methods such as breath test and urease test, which are adopted alternatively to histological examination, can delay the diagnosis of early lymphomas. On the other hand the proved regression of gastric low grade Malt lymphomas after a successful HP eradication strongly suggests the need for early diagnosis. The aim of this study was to report the results of our experience with regard to clinical, endoscopic, histopathologic, and immunohistochemical features of gastric MALT lymphomas. We studied twenty-seven consecutive cases of gastric Malt lymphoma. HP presence in gastric mucosa was detected in all cases but endoscopy only in 40.7% of cases giving a diagnosis of suspected malignancy. In conclusion, it is very important to sample gastric mucosa in HP positive patients because the histological examination represents the most effective tool to detect lesions at the earliest and curable stage.
通过呼气试验和尿素酶试验等非侵入性方法检测幽门螺杆菌（HP）感染，可替代组织学检查，这可能会延迟早期淋巴瘤的诊断。另一方面，成功根除HP后胃低度黏膜相关淋巴组织（MALT）淋巴瘤得到证实的消退强烈提示早期诊断的必要性。本研究的目的是报告我们在胃MALT淋巴瘤的临床、内镜、组织病理学和免疫组化特征方面的经验结果。我们研究了连续27例胃MALT淋巴瘤病例。所有病例均检测到胃黏膜中存在HP，但仅40.7%的病例通过内镜检查诊断为疑似恶性肿瘤。总之，对HP阳性患者的胃黏膜进行采样非常重要，因为组织学检查是在最早且可治愈阶段检测病变的最有效工具。
