Myers M G, Alnemri K
Division of Cardiology, Sunnybrook Health Science Centre, Toronto, Ontario.
Can J Cardiol. 1998 Nov;14(11):1363-6.
Atrial fibrillation (AF) is a common complication of coronary artery bypass surgery (CABS). Because conventional antiarrhythmic therapy may cause proarrhythmia, a rate control approach to AF was evaluated in 59 patients post-CABS. The use of digoxin with or without verapamil for AF was associated with spontaneous conversion to normal sinus rhythm in 55 of 59 patients. Two to four weeks later, all patients were on digoxin and 12% were on verapamil, with two of four AF patients having converted to normal sinus rhythm and two others previously in normal sinus rhythm now in AF. A rate control approach to treating AF post-CABS resulted in over 90% of patients being in normal sinus rhythm for two to four weeks after the onset of the arrhythmia.
心房颤动（AF）是冠状动脉旁路移植术（CABS）的常见并发症。由于传统抗心律失常治疗可能会引发心律失常，因此对59例CABS术后患者采用了心率控制方法来治疗房颤。在59例患者中，55例使用地高辛联合或不联合维拉帕米治疗房颤后自发转为正常窦性心律。两到四周后，所有患者均服用地高辛，12%的患者服用维拉帕米，4例房颤患者中有2例转为正常窦性心律，另外2例之前为正常窦性心律的患者现处于房颤状态。对CABS术后房颤采用心率控制方法治疗，结果显示心律失常发作后两到四周内，超过90%的患者处于正常窦性心律。
