Wilmink A B, Pleumeekers H J, Hoes A W, Hubbard C S, Grobbee D E, Quick C R
Institute of Public Health, University of Cambridge, U.K.
Eur J Vasc Endovasc Surg. 1998 Nov;16(5):431-7. doi: 10.1016/s1078-5884(98)80013-0.
To resolve whether the infrarenal aortic diameter (IAD) continues to increase throughout life; to ascertain the relationship between IAD and age, sex, body size, and smoking status, and to determine whether these factors influence the IAD over the entire range of aortic diameters or only in a proportion.
Combined cross-sectional data from two population-based screening programmes for abdominal aortic aneurysms (AAA) in Huntingdon (U.K.) and Rotterdam (The Netherlands).
The antero-posterior diameter of the infrarenal aorta was measured. The influences of age, gender, body size and smoking status were examined.
Data were analysed from 3066 women and 8270 men. In men, mean IAD rose from 20.7 mm to 23.5 mm in the older age groups. However, IADs remained constant below the 75th perentile in men and the 85th percentile in women. Similarly only the top 15-25% of the aortic diameters were larger in smokers compared with non-smokers.
The aortic diameter increased with age in only a minority of the population. Furthermore, known risk factors for AAA contributed to aortic dilatation in only the upper tail of the frequency distribution. Thus only 25% of men and 15% of women may be prone to aortic dilatation.
确定肾下腹主动脉直径（IAD）在一生中是否持续增加；确定IAD与年龄、性别、体型和吸烟状况之间的关系，并确定这些因素是在整个主动脉直径范围内还是仅在一定比例上影响IAD。
来自英国亨廷顿和荷兰鹿特丹两项基于人群的腹主动脉瘤（AAA）筛查项目的综合横断面数据。
测量肾下腹主动脉的前后径。研究年龄、性别、体型和吸烟状况的影响。
对3066名女性和8270名男性的数据进行了分析。在男性中，老年组的平均IAD从20.7毫米升至23.5毫米。然而，男性IAD在第75百分位数以下以及女性在第85百分位数以下保持不变。同样，吸烟者的主动脉直径仅在最大的15%-25%中大于非吸烟者。
仅少数人群的主动脉直径随年龄增加。此外，已知的AAA危险因素仅在频率分布的上尾部分导致主动脉扩张。因此，只有25%的男性和15%的女性可能易患主动脉扩张。
