Kelly B, Raphael B, Judd F, Perdices M, Kernutt G, Burnett P, Dunne M, Burrows G
Department of Psychiatry, University of Queensland, Brisbane, Australia.
Gen Hosp Psychiatry. 1998 Nov;20(6):345-52. doi: 10.1016/s0163-8343(98)00042-5.
This study investigated the psychological impact of HIV infection through assessment of posttraumatic stress disorder in response to HIV infection. Sixty-one HIV-positive homosexual/bisexual men were assessed for posttraumatic stress disorder in response to HIV infection (PTSD-HIV) using a modified PTSD module of the DIS-III-R. Thirty percent met criteria for a syndrome of posttraumatic stress disorder in response to HIV diagnosis (PTSD-HIV). In over one-third of the PTSD cases, the disorder had an onset greater than 6 months after initial HIV infection diagnosis. PTSD-HIV was associated with other psychiatric diagnoses, particularly the development of first episodes of major depression after HIV infection diagnosis. PTSD-HIV was significantly associated with a pre-HIV history of PTSD from other causes, and other pre-HIV psychiatric disorders and neuroticism scores, indicating a similarity with findings in studies of PTSD from other causes. The findings from this preliminary study suggest that a PTSD response to HIV diagnosis has clinical validity and requires further investigation in this population and other medically ill groups. The results support the inclusion of the diagnosis of life-threatening illness as a traumatic incident that may lead to a posttraumatic stress disorder, which is consistent with the DSM-IV criteria.
本研究通过评估因感染艾滋病毒而产生的创伤后应激障碍，调查了艾滋病毒感染对心理的影响。使用DIS-III-R的改良创伤后应激障碍模块，对61名艾滋病毒呈阳性的同性恋/双性恋男性进行了因感染艾滋病毒而产生的创伤后应激障碍（PTSD-HIV）评估。30%的人符合因艾滋病毒诊断而产生的创伤后应激障碍综合征（PTSD-HIV）的标准。在超过三分之一的创伤后应激障碍病例中，该障碍在首次诊断艾滋病毒感染后6个月以上才出现。PTSD-HIV与其他精神疾病诊断相关，特别是在艾滋病毒感染诊断后首次出现重度抑郁症。PTSD-HIV与因其他原因导致的艾滋病毒感染前创伤后应激障碍病史、其他艾滋病毒感染前精神疾病以及神经质得分显著相关，这表明与其他原因导致的创伤后应激障碍研究结果相似。这项初步研究的结果表明，对艾滋病毒诊断的创伤后应激障碍反应具有临床有效性，需要在该人群和其他患病群体中进一步研究。结果支持将危及生命的疾病诊断作为可能导致创伤后应激障碍的创伤事件，这与《精神疾病诊断与统计手册》第四版标准一致。
